88 Food Allergy and Sensitivity Test (F.A.S.T)

Allergies and sensitivities in response to foods may cause a variety of symptoms within the body ranging from mildly uncomfortable to severe and life-threatening. This Infinite Allergy “88 Food Allergy and Sensitivity Test” (F.A.S.T) includes IgG, C3d/C3b, IgE, and IgG4.

IgE (immunoglobulin E) allergies are the immediate responses to a foreign substance that has entered the body via food or inhalation. IgE allergies can cause very serious symptoms like difficulty in breathing, swelling, and hives. In more serious cases, IgE reactions can lead to anaphylactic shock. Our test measures the blood level of IgE, one of the five subclasses of antibodies. Antibodies are proteins made by the immune system that attack antigens such as bacteria, viruses, and allergens.

They can become confused or cross-reactive and begin attacking foods instead. High titers of IgE are associated with allergic reactions, which is when the immune system overreacts to environmental antigens such as pollen, pet dander, and/or parasitic infections.

IgG (immunoglobulin G, total) are antibodies that provide long-term resistance to infections and have a much longer half-life than an IgE allergy. This food sensitivity can be more subtle, and many people live with it for years, if not their entire lives. Sensitivity symptoms range from fatigue, headache/nausea, seizures, hyperactivity, bloating, mood changes, or dark circles under the eyes. IgG symptoms typically occur within 3-72 hours after the offending food was ingested and they will create ongoing inflammation that can make most conditions worse. Because they can present at such varied times, it is hard to isolate from a diet history alone, and testing becomes particularly useful. 

The degree and severity of symptoms vary greatly from person to person because of genetic makeup. The complete elimination of IgG positive foods may bring about important improvements in symptoms of irritable bowel syndrome, autism, ADHD, cystic fibrosis, rheumatoid arthritis, and epilepsy, as demonstrated in numerous clinical studies. It is important to get tested for food sensitivities to know what foods work for the patient’s body and what foods don’t. If you are only looking at allergies, or IgE, then you would miss the IgG mediated symptoms, creating an incomplete patient picture.

C3 (complement component 3) is a protein of the innate immune system that is activated by microorganisms in the absence of an antibody. When C3d is activated in response to an antigen, the C3 portion attaches to the antigen. This activation, even though it is independent, will amplify the reaction that occurs with total IgG greatly increasing inflammation and symptoms of sensitivity. This same reaction that was designed to amplify inflammation to microorganisms, can be triggered in response to foods. If complement is present, it will amplify an IgG reaction as much as 1000 to 10,000-fold. Therefore, tests that only measure IgG may miss the reactions to foods that are most clinically relevant. C3 will be cleaved into multiple C3 breakdown products, and all of these play a role in increasing inflammatory response to foods. 

IgG4 (immunoglobulin G, subtype 4): is another antibody produced in the body to fight infection.  Desensitization injections, or allergy therapies, increase IgG4 to help neutralize the reaction of IgE. This is because of its potential to decrease histamine responses by blocking IgE from attaching to receptors, causing degranulation. Levels of IgG4 are beneficial up to a point, as they block IgE or allergic reactions and result in immune tolerance to foods.

Please note that the purchase of the following tests: 88 Food Allergy and Sensitivity, OAT, GI MAP and DUTCH Complete require physical test kits to be shipped to your home to complete testing. Once your order is submitted, you will receive a tracking number for your shipment from DHA Laboratory, and your kits will arrive with everything needed to get started.

The purchase of the Nohr-Functional Wellness Panel requires you to complete testing at a local draw site. You will not need a physical test kit to complete your draw. To complete your order for any of the tests mentioned above, please fill out the billing, shipping, and payment fields below. DHA Laboratory will send you a list of local laboratories and instructions to complete your blood draw via email.

If you have any questions about the tests, the testing process, or need help with your lab order at any time, please feel free to contact DHA Laboratory. T: (847) 222-9546 / E: info@dhalab.com

**Note: All laboratory testing requires an authorizing physician. DHA Laboratory offers a patient direct program that partners you with an authorizing physician. If you have any additional questions regarding the availability of testing, please contact our laboratory by telephone or email.

[Sample Type: Blood, Urine, Stool]
[Turnaround time (LabCorp): 5-7 Business days]
[Turnaround time (Physical test kits): 2-3 Weeks]
[Performing Lab: Infinite Allergy Labs, LabCorp, Mosaic Diagnostics, Diagnostic Solutions, Precision Analytical]