Histamine and Intestinal Permeability Test

Advanced Intestinal Barrier Assessment

The Precision Point Diagnostics Advanced IBA profile takes a deep dive into intestinal barrier function. Using a collection of innovative biomarkers, this test helps clinicians determine if their patients have intestinal permeability, or “leaky gut.” Intestinal permeability has been suggested as a root cause of autoimmune diseases, systemic inflammation, and food sensitivities. Healing the gut barrier is so pivotal for resolving chronic disease that if it isn’t addressed, other treatments will have little to no effect.

The Advanced IBA profile stands out for its unique, clinically relevant markers which tell a complex story about gut barrier health. Histamine and diamine oxidase (DAO) give information about histamine balance and gut mucosal health. Plasma Zonulin is a well-documented marker of intestinal tight junctions and is the preferred specimen for assessment. Lipopolysaccharides (LPS) are endotoxins produced by gram-negative bacteria. LPS antibodies give information about inflammation and intestinal permeability. Patients with allergies, food sensitivities, digestive symptoms, headache, cognitive decline, depression, and more can benefit from the Advanced IBA profile (see Table of Associated Symptoms and Conditions).

Advanced Intestinal Barrier Assessment


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