**Note: All laboratory testing requires an authorizing physician. DHA Laboratory offers a patient direct program that partners you with an authorizing physician. If you have any additional questions regarding the availability of testing, please contact our laboratory by telephone or email.**
Histones are lysine-rich and arginine-rich basic proteins of eukaryotic cells which are found as complexes with DNA. Antibodies to histones are detected in approximately 30%- 60% of patients with systemic lupus erythematosus (SLE), however their presence in about 95% of patients with drug-induced lupus is more important diagnostically.