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Lab Testing


Cardiovascular Risk Profile

Doctors Data

SKU: 1414


Product Description

**NOTE: All laboratory testing requires an authorizing physician in order to complete the laboratory testing.**

Cardiovascular Risk Profile

Cardiovascular disease (CVD) is associated with more deaths than all cancers—and more deaths in women than breast cancer. This Cardiovascular Risk Profile evaluates a thorough battery of traditional and advanced biomarkers to aid in early detection and modification of risk factors. Doctor’s Data measures oxidized LDL, small dense LDL and Lp(a), which are higher in CVD patients and correlated with the severity of CVD. A total of 11 primary and secondary risk factors are evaluated to provide actionable information at a tremendous value.

Turnaround Time

5 to 7 days

Analytes Tested

Apolipoprotein, A1; serum
Apolipoprotein, B, serum
C-Reactive Protein; serum
Cholesterol; serum
HDL; serum
Homocysteine; serum
LDL; serum
Lipoprotein (a), serum
Oxidized LDL; serum
Triglycerides; serum
small dense LDL; serum

This test is useful for

  • Cardiovascular Disease
  • Lipid/Lipoprotein Profile
  • Heart Attack
  • Peripheral Arterial Disease
  • Stroke
  • Cardioprotective Nutrient Status
  • Inflammation

Detailed Information

Cardiovascular disease (CVD) is associated with more deaths than all cancers—and more deaths in women than breast cancer. The Cardiovascular Risk Profile from Doctor’s Data reviews a thorough battery of biomarkers to aid in early detection and reduction of risk factors before the disease progresses.

Risk Factors and Analysis

Lipoprotein-Related Biomarkers
Total and LDL cholesterol, total triglycerides and HDL cholesterol have traditionally been measured to gauge CVD risk. However, recent research indicates that more focused biomarkers can provide even greater insight.

For example, oxidized LDL is plaque-specific and directly involved in accelerated atherogenesis and late-stage atherosclerotic plaque instability and rupture. Small dense LDL exhibits greater penetration into the arterial wall and has a longer half-life as well as lower resistance to oxidation compared to that of large buoyant LDL. Circulating levels of these two markers are:

1.  Strong independent CVD risk factors
2.  Higher in CVD patients
3.  Correlated with the severity of CVD
4.  Not correlated with LDL cholesterol levels

In addition, levels of apolipoproteins A-1 and B, specific protein constituents of HDL and LDL, are also strong indicators of risk.

Doctor’s Data profiles evaluate each of these biomarkers as well as ratios of atherogenic to anti-atherogenic lipids, lipoproteins and apolipoproteins for further insight.

Arterial damage is associated with the infiltration of white cells into vessel walls and inflammation, which increases blood levels of two acute phase proteins, C-reactive protein and ferritin. For example, patients with moderately elevated CRP are more likely to develop stroke, myocardial infarction and severe peripheral arterial disease. Although not specific to CVD, analysis of high sensitivity to these two proteins is valuable in a comprehensive assessment of CVD risk.

Performing Laboratory: Doctors Data


Instructions (PDF)
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Sample Report

Sample Report (PDF)
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