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Lab Testing

Intestinal Permeability


SKU: 3636


Product Description

Intestinal Permeability

This test measures the ability of two sugar molecules, lactulose and mannitol, to permeate the intestinal epithelial barrier. Ordinarily, mannitol is efficiently absorbed but lactulose, a larger molecule, is not. This test can help to identify malabsorption and “leaky gut” syndrome (abnormal intestinal permeability), which is often associated with inflammation specifically in the gastrointestinal tract. This test requires a baseline urine collection followed by a six-hour timed urine collection after ingesting a lactulose and mannitol solution.

Turnaround Time

3 to 5 days

Analytes Tested

Analyte CPT ABN Required
Lactulose 84379 No
Mannitol 84379 No

This test is useful for

  • Gastrointestinal Symptoms
  • Food Sensitivities
  • Inflammation
  • Malabsorption
  • Nutritional Deficiencies


Instructions (PDF)
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Sample Report

Sample Report (PDF)
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