**Note: All laboratory testing requires an authorizing physician. DHA Laboratory offers a patient direct program that partners you with an authorizing physician. If you have any additional questions regarding the availability of testing, please contact our laboratory by telephone or email.**
Levels of SHBG are under positive control of estrogens and thyroid hormones and are suppressed by androgens. These influences control the liver synthesis of this carrier protein. Decreased levels of SHBG are often found in hirsutism, virilization, obese postmenopausal women, and in women with prevalent hair loss. Increased levels are sometimes present in cases of hyperthyroidism, testicular feminization, cirrhosis, male hypogonadism, pregnancy, women using oral contraceptives, and prepubertal children.
Patient Preparation: Discontinue any supplements containing Biotin for 72 hours prior to specimen collection.